Short term physical exercise leads to a small troponin increase measurable with a high-sensitive cardiac troponin I assay
نویسندگان
چکیده
منابع مشابه
Highly sensitive cardiac troponin I assay leads to lowered specificity.
I read with great interest the article of Kavsak et al. (1 ) on the utility of a next-generation high-sensitivity Beckman Coulter cardiac troponin I (cTnI) assay with a 20% CV at 2.95 ng/L. This approach demonstrated a higher diagnostic sensitivity (81% vs 62%) for myocardial injury with a changing pattern of cTnI values, compared with the AccuTnI assay cleared by the US Food and Drug Administr...
متن کاملHigh-sensitive cardiac troponin T
Cardiac troponin is the preferred biomarker for the diagnosis of acute myocardial infarction (AMI). The recent development of a high-sensitive cardiac troponin T (hs-cTnT) assay permits detection of very low levels of cTnT. Using the hs-cTnT assay improves the overall diagnostic accuracy in patients with suspected AMI, while a negative result also has a high negative predictive value. The gain ...
متن کاملShort- and long-term biological variation in cardiac troponin I measured with a high-sensitivity assay: implications for clinical practice.
BACKGROUND The improved detection limit and precision in new-generation commercial assays for cardiac troponin I (cTnI) have lowered the 99th-percentile cutoff value, yielding higher frequencies of positive test results. Because serial testing is important in interpreting low concentrations, we evaluated the biological variation of cTnI in both the short (hours) and long (weeks) terms and deter...
متن کاملA Rational Adoption of the High Sensitive Assay for Cardiac Troponin I in Diagnostic Routine
We describe the adoption of high sensitive troponin I (hsTnI) in clinical practice in two hospital settings in Italy. Samples from 426 consecutive patients (mean age 68.8 ± 17.0) admitted to the Emergency Department with a suspected acute coronary syndrome (ACS) have been tested at admittance and after 3 and 6 hours by contemporary TnI and hsTnI. Results have been compared to the final clinical...
متن کاملShort- and Long-Term Biological Variation in Cardiac Troponin I with a High-Sensitivity Assay: Implications for Clinical Practice
BACKGROUND: The improved detection limit and precision in new-generation commercial assays for cardiac troponin I (cTnI) have lowered the 99th-percentile cutoff value, yielding higher frequencies of positive test results. Because serial testing is important in interpreting low concentrations, we evaluated the biological variation of cTnI in both the short (hours) and long (weeks) terms and dete...
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ژورنال
عنوان ژورنال: European Heart Journal
سال: 2013
ISSN: 0195-668X,1522-9645
DOI: 10.1093/eurheartj/eht309.p4008